The paper describes the synthesis of two epimeric tdpeptides &(L-cx-aminoadipoyl)-L-cysteinyI-D-(Omethyl)-D-threonine (13) and &(L-ct-aminoadipoyl)-L-cysteinyl-D-(O-methyl)-D-allothreonine ( 14), modified substrates for the isopenicillin-N synthase enzyme. The D-allothreonine tripeptide ( 14) has be
ChemInform Abstract: Synthesis of δ-(L-α-Aminoadipoyl)-L-cysteinyl-D- (O-methyl)-D-allothreonine a Substrate for Isopenicillin-N Synthase and Its O-Methyl-D-threonine Epimer.
✍ Scribed by S. PETURSSON; J. E. BALDWIN
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 40 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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