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Electrolytic lesion of globus pallidus ameliorates the behavioral effects of quinolinic acid lesion of the striatum: A potential novel treatment in a rat model of Huntington's disease

✍ Scribed by L. Ayalon; D. Joel; R. Tarrasch; J. Feldon; I. Weiner


Book ID
117476223
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
18 KB
Volume
237
Category
Article
ISSN
0304-3940

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Deficits induced by quinolinic acid lesi
✍ Daphna Joel; Liat Ayalon; Ricardo Tarrasch; Ina Weiner πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 241 KB πŸ‘ 1 views

## Abstract Symptoms in the early stages of Huntington's disease (HD) are assumed to reflect basal ganglia circuit dysfunction secondary to degeneration of striatal projections to the external segment of the globus pallidus (GPe). The hypothesis that GPe lesion would ameliorate HD symptoms by β€œnorm