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Amelioration of behavioral deficits in a rat model of Huntington's disease by an excitotoxic lesion to the globus pallidus

✍ Scribed by Liat Ayalon; Ravid Doron; Ina Weiner; Daphna Joel


Book ID
117101043
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
567 KB
Volume
186
Category
Article
ISSN
0014-4886

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## Abstract Symptoms in the early stages of Huntington's disease (HD) are assumed to reflect basal ganglia circuit dysfunction secondary to degeneration of striatal projections to the external segment of the globus pallidus (GPe). The hypothesis that GPe lesion would ameliorate HD symptoms by β€œnorm

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