Amelioration of behavioral deficits in a rat model of Huntington's disease by an excitotoxic lesion to the globus pallidus
β Scribed by Liat Ayalon; Ravid Doron; Ina Weiner; Daphna Joel
- Book ID
- 117101043
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 567 KB
- Volume
- 186
- Category
- Article
- ISSN
- 0014-4886
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π SIMILAR VOLUMES
## Abstract Symptoms in the early stages of Huntington's disease (HD) are assumed to reflect basal ganglia circuit dysfunction secondary to degeneration of striatal projections to the external segment of the globus pallidus (GPe). The hypothesis that GPe lesion would ameliorate HD symptoms by βnorm
Objective. To noninvasively examine the pathogenesis of rat adjuvant-induced arthritis (AIA) by magnetic resonance imaging (MRI), and to correlate MRI indices of disease progression with classic inflammatory parameters and histologic evaluation. Methods. AIA was established in male Lewis rats follo