Spectral data provide the first evidence that lactoperoxidase, a model enzyme for most mammalian peroxidases, catalyzed the one-electron oxidation and/or peroxidation of 5,7-dihydroxytryptamine. This process correlates with the production of superoxide radicals as is evident from the observed inhibi
Electro-oxidation of the neurotoxin 5,6-dihydroxytryptamine and effects of its oxidation products in mice
โ Scribed by Rajendra N. Goyal; Dinesh K. Garg
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 721 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1567-5394
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๐ SIMILAR VOLUMES
Electrochemical oxidation of 4-hydroxyindole has been studied at pyrolytic graphite electrode in aqueous phsophate buffers of pH 2.1-10.1. Oxidation has been found to proceed in a single well-defined peak. The number of electrons involved under CV conditions were found as 1.3 ฯฎ 0.1 and were differen
Head-twitch response (HTR) in mice was induced by intracerebroventricular injection of tryptamine (TRA) as well as serotonin (5-HT) and p-chloroamphetamine (PCA). Pretreatment with 5,7-dihydroxytryptamine enhanced both the 5-HT-induced and the TRA-induced HTR. The PCA-induced HTR, however, was atten