## Abstract Oxydation of **2** with iodine followed by acylation leads to β‐lactamdisulfides of type **3**. Compounds **3** can be transformed into alcohols **4** by reductive alkylation with ethylenoxide and zinc/acetic acid. Compounds **4** are used as starting materials for the synthesis of N‐ac
Ein einfacher Zugang zu 3-Amino-nocardicinsäure. Modifikationen von Antibiotika. 17. Mitteilung [1]
✍ Scribed by Karl Schaffner-Sabba; Beat W. Müller; Riccardo Scartazzini; Hansuli Wehrli
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- German
- Weight
- 339 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
A Simple Route to 3‐Amino‐nocardicinic Acid
Starting from nocardicin A (1), a novel and efficient procedure for the preparation of 3‐amino‐nocardicinic acid (4) and its protected derivatives 6 and 8–11 is described.
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