✦ LIBER ✦
Steroide und Sexualhormone 242. Mitteilung [1] herstellung von 14β-hydroxy-20-keto-δ16-steroiden: Ein neuer ergiebiger zugang zu 3-O-methyl-17α, 20ξ-tetrahydrobatrachotoxinin A
✍ Scribed by Frl. E. Gössinger; W. Graf; R. Imhof; H. Wehrli
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- German
- Weight
- 291 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A novel method for the reductive epoxide opening in a 14β, 15β‐epoxy‐20‐oxo‐Δ^16^‐pregnene 4 affords an almost quantitative yield of the 14β‐hydroxy‐20‐oxo‐Δ^16^‐pregnene 5. This leads to a considerable improvement of the formerly published synthesis of 3‐O‐methyl 17 α, 20ξ‐tetrahydrobatrachotoxinin A (2) [3].