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Efficient Synthesis of the C 1 −C 11 Fragment of the Tedanolides. The Nonaldol Aldol Process in Synthesis

✍ Scribed by Jung, Michael E.; Marquez, Rodolfo


Book ID
127229818
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
60 KB
Volume
2
Category
Article
ISSN
1523-7060

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Use of the non-aldol aldol process in th
✍ Michael E Jung; Christopher P Lee 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 107 KB

The use of a lactol methyl ether 23 in place of the simple tetrahydrofuran 11 allows for the high yielding non-aldol aldol process to occur without concomitant tetrahydropyran formation (cf. 13) to give the desired product 24 in good yield.