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Efficient Synthesis of (.+-.)-Juglomycin A.

โœ Scribed by Jong-Pil Min; Ju-Cheun Kim; Oee-Sook Park


Book ID
101962450
Publisher
John Wiley and Sons
Year
2004
Weight
135 KB
Volume
35
Category
Article
ISSN
0931-7597

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A highly enantioselective synthesis of (ร€)-and (+)-juglomycin A, a quinone antibiotic is described. The synthesis is completed in eight steps, and 19% overall yield and in a high enantioselectivity of 99.5% [for (ร€)-juglomycin A] and 98.5% [for (+)-juglomycin A]. The synthetic strategy features an e