A new efficient synthesis of 11-aza ster
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Frédéric Cachoux; Malika Ibrahim-Ouali; Maurice Santelli
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Article
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2001
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Elsevier Science
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French
⚖ 99 KB
The total synthesis and stereochemistry of new 11-aza steroids are reported. Our strategy involves an intramolecular Diels-Alder cycloaddition of o-quinodimethanes which are generated by thermal ring opening of a benzocyclobutene.