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A new efficient synthesis of 11-aza steroids

✍ Scribed by Frédéric Cachoux; Malika Ibrahim-Ouali; Maurice Santelli

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
99 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

The total synthesis and stereochemistry of new 11-aza steroids are reported. Our strategy involves an intramolecular Diels-Alder cycloaddition of o-quinodimethanes which are generated by thermal ring opening of a benzocyclobutene.

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