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Efficient Synthesis of (2 S ,3 S )-2-Ethyl-3-methylvaleramide Using (1 S ,2 S )-Pseudoephedrine as a Chiral Auxiliary

✍ Scribed by Li, Bin-Feng; Hughes, Robert M.; Le, Jackie; McGee, Kevin; Gallagher, Donald J.; Gross, Raymond S.; Provencal, David; Reddy, Jayachandra P.; Wang, Peng; Zegelman, Lev; Zhao, Yuxin; Zook, Scott E.


Book ID
118070340
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
130 KB
Volume
13
Category
Article
ISSN
1083-6160

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## Abstract A several novel 1,3,4‐oxadiazinan‐2‐thiones have been synthesized by the cyclization of β‐hydrazino‐alcohols with either carbon disulfide or 1,1′‐thiocarbonyldiimidazole (TCDI).