ChemInform Abstract: Enantioselective Synthesis of 2-Substituted Alcohols Using (+)-(1S,2S)-Pseudoephedrine as Chiral Auxiliary.
β Scribed by Lutz F. Tietze; Christian Raith; C. Christian Brazel; Soeren Hoelsken; Joerg Magull
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 35 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Chiral hydrazones 1 reacted with aryl- or alkyl-lithiums at -78 degrees C in a short reaction time, within 10 min, to afford arylated or alkylated chiral hydrazines 3 with extremely high diastereoselectivity (up to >99% de) and high chemical yields. The hydrazines are readily converted to chiral ami
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## Abstract For Abstract see ChemInform Abstract in Full Text.
1998 alcohols alcohols (acyclic compounds) P 0110 33 -116 (S)-2-(Dibenzylamino)-3-phenylpropanal as a Chiral Auxiliary: A New Strategy for the Asymmetric Synthesis of 2-Substituted Alcohols. -The key steps in the synthesis of the title alcohols are nucleophilic addition to the aldehyde (I), which p