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Efficient Synthesis and Cell-Transfection Properties of a New Multivalent Cationic Lipid for Nonviral Gene Delivery

✍ Scribed by Ewert, Kai; Ahmad, Ayesha; Evans, Heather M.; Schmidt, Hans-Werner; Safinya, Cyrus R.


Book ID
125975612
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
251 KB
Volume
45
Category
Article
ISSN
0022-2623

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New multivalent cationic lipids reveal b
✍ Ayesha Ahmad; Heather M. Evans; Kai Ewert; Cyril X. George; Charles E. Samuel; C πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 340 KB

## Abstract ## Background Gene carriers based on lipids or polymersβ€”rather than on engineered virusesβ€”constitute the latest technique for delivering genes into cells for gene therapy. Cationic liposome–DNA (CL‐DNA) complexes have emerged as leading nonviral vectors in worldwide gene therapy clinic