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pH-Sensitive Pegylated Cationic Lipid-DNA Complexes for Gene Delivery: Transfection Efficiency and Live Cell Imaging Studies

✍ Scribed by Chan, Chia-Ling; Majzoub, Ramsey; Shirazi, Rahau S.; Liang, Keng-San; Ewert, Kai K.; Safinya, Cyrus R.

Book ID
122246398
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
72 KB
Volume
102
Category
Article
ISSN
0006-3495

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## Abstract ## Background Gene carriers based on lipids or polymers—rather than on engineered viruses—constitute the latest technique for delivering genes into cells for gene therapy. Cationic liposome–DNA (CL‐DNA) complexes have emerged as leading nonviral vectors in worldwide gene therapy clinic