Three new gradient-selected NMR experiments for the analysis of long-range heteronuclear coupling constants are presented. They are demonstrated on a series of compounds including sucrose, strychnine and a complex macrolide, phormidolide, isolated from a marine cyanobacterium. These 1D and 2D hetero
Efficient measurement of the sign and the magnitude of long-range proton-carbon coupling constants from a spin-state-selective HSQMBC-COSY experiment
✍ Scribed by Josep Saurí; Teodor Parella
- Book ID
- 115521677
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 258 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.3867
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## Abstract New spin‐state‐selective (S^3^) NMR pulse sequences exclusively applying cross‐polarization schemes to achieve optimum homonuclear and heteronuclear ^1^HX coherence transfer are reported for the simple and accurate measurement of the magnitude and sign of heteronuclear coupling constan
A new technique is described which enables accurate values of heteronuclear long-range coupling constants to be obtained from highly distorted multiplets in two-dimensional correlation spectra. The technique uses a simple data fitting of the distorted multiplet with a model obtained from the convent