Efficient dehydrocyanation of hindered 1-substituted olefins

✍ Scribed by O. Temmem; D. Uguen; A. De Cian; N. Gruber

• Book ID: 104250935
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 94 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)00516-6

✦ Synopsis

The chlorosulfides 7 which formed quantitatively by reaction of olefins 5 with PhSCl under neutral conditions could be converted into the unsaturated nitriles 6 in good yields by sequential treatment with alkaline cyanides and MCPBA, a similar result being observed by reversing this order.