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Synthesis of Hindered and Functionalized 1-CF 3 Substituted Olefins via a Carbolithiation−Elimination−Metalation Cascade

✍ Scribed by Bégué, Jean-Pierre; Bonnet-Delpon, Danièle; Bouvet, Denis; Rock, Michael H.


Book ID
127393876
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
191 KB
Volume
61
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Synthesis of Hinder
✍ J.-P. BEGUE; D. BONNET-DELPON; D. BOUVET; M. H. ROCK 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB

Synthesis of Hindered and Functionalized 1-CF3 Substituted Olefins via a Carbolithiation-Elimination-Metalation Cascade. -Trisubstituted fluoroalkenes of type (III) are obtained stereoselectively. They react further with organolithium reagents and undergo vinyl metalation to give, after trapping wi