Efficient Chemoenzymatic Synthesis of Chiral Pincer Ligands
✍ Scribed by Felluga, Fulvia; Baratta, Walter; Fanfoni, Lidia; Pitacco, Giuliana; Rigo, Pierluigi; Benedetti, Fabio
- Book ID
- 124083311
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 199 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0022-3263
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## Abstract **Feel the pinch!** Planar–chiral, cationic, ruthenium–palladium complexes based on η^6^,η^1^‐coordinated ECE′ pincer ligands are synthesized as racemic mixtures by reacting ECE′–palladium complexes and [Ru(C~5~R~5~)(MeCN)~3~]^+^ arenophiles (R=H or Me). Chiral resolution of the cationi
A series of chiral enones was successfully synthesized from chemoenzymatically produced chiral diols. These chiral enones are highly functionalized synthons, which can be used in the total synthesis of natural products such as forskolin and avermectins.