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Efficacy of Human Recombinant DNase in Pediatric Patients with Cystic Fibrosis

✍ Scribed by Marı́a Elena Y Furuya; José Luis Lezana-Fernández; Mario H Vargas; Juan Francisco Hernández-Sierra; Jorge Luis Ramı́rez-Figueroa

Book ID
114179831
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
89 KB
Volume
32
Category
Article
ISSN
0188-4409

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Cystic fibrosis is characterized by the accumulation of thick viscous purulent secretions. Recombinant human deoxyribonuclease I (rhDNase) breaks down extracellular DNA, which contributes to the increased viscosity of sputum. A multinational, open-label study was conducted in 974 cystic fibrosis pat