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Two years experience with recombinant Human DNase I in the treatment of pulmonary disease in cystic fibrosis

โœ Scribed by P.L. Shah; S.F. Scott; D.M. Geddes; M.E. Hodson


Book ID
116164208
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
361 KB
Volume
89
Category
Article
ISSN
0954-6111

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Cystic fibrosis is characterized by the accumulation of thick viscous purulent secretions. Recombinant human deoxyribonuclease I (rhDNase) breaks down extracellular DNA, which contributes to the increased viscosity of sputum. A multinational, open-label study was conducted in 974 cystic fibrosis pat