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Efficacy of Entecavir and Adefovir Combination Therapy for Patients with Lamivudine- and Entecavir-Resistant Chronic Hepatitis B

✍ Scribed by Jung Won Jeon; Hyun Phil Shin; Joung Il Lee; Kwang Ro Joo; Jae Myung Cha; Jae Jun Park; Jun Uk Lim; Kyuseong Lim; Sunyong Kim


Book ID
113064268
Publisher
Springer US
Year
2011
Tongue
English
Weight
199 KB
Volume
57
Category
Article
ISSN
0163-2116

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## Abstract There is little clinical information on the management of hepatitis B virus (HBV) that is resistant to multiple drugs including entecavir (ETV). The present retrospective cohort study assessed the antiviral efficacy of ETV/adefovir dipivoxil (ADV) combination therapy for ETV‐resistant H

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This study evaluated the efficacy of adefovir (ADV) plus lamivudine (LAM) or ADV add-on therapy for patients with entecavir (ETV)-refractory hepatitis B infection. Twenty-nine ETVresistant and 8 patients with suboptimal response to ETV were enrolled. Twenty-seven patients received ADV ΓΎ LAM therapy