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Efficacy Comparison of Scopolamine and Diazepam against Soman-Induced Debilitation in Guinea Pigs

✍ Scribed by D.R. Anderson; C. Gennings; W.H. Carter; L.W. Harris; W.J. Lennox; S.L. Bowersox; R.P. Solana

Book ID
115608320
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
343 KB
Volume
22
Category
Article
ISSN
0272-0590

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Prophylactic transdermal treatment with
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This study was designed to evaluate the prophylactic efficacy of transdermally administered physostigmine (PHY) against soman exposure using guinea-pigs. Transdermal PHY pad (3 cm2 kg-'; 60 p g cm-2), containing a vehicle based on propionic acid, was applied onto the dorsal back of the animals, 24 h