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Effects ofd,l-propanolol on open field behavior of rats

✍ Scribed by A. Poli; J. Palermo-Neto

Publisher: Springer
Year: 1985
Tongue: English
Weight: 317 KB
Volume: 86
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00431701

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✦ Synopsis

Rats were administered with different doses of d,/-propranolol or d,l-propranolol plus amphetamine before open-field observations. Results show that d,/-propranolol decreased locomotion and rearing frequencies and increased immobility duration in rats. An antagonism between the effects of amphetamine and d,/-propranolol on general activity of rats was also observed. Results are discussed in the light of a possible interference of the drugs with the activity of either noradrenergic neurons or midbrain reticular formation.

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