Effects of the Val158Met catechol-O-methyltransferase polymorphism on cortical structure in children and adolescents
โ Scribed by Shaw, P; Wallace, G L; Addington, A; Evans, A; Rapoport, J; Giedd, J N
- Book ID
- 109889822
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 100 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1359-4184
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ## Objective Genetic polymorphisms of the noradrenergic pathway can be factors to predict the effect of antidepressants when their pharmacological mechanisms of action include the noradrenergic system. The purpose of the present study was to determine whether the tyrosine hydroxylase (
## Abstract ## Background: The Aโallele of the catecholโ__O__โmethyltransferase (__COMT__) Val158Met polymorphism is associated with decreased enzymatic activity and higher dopamine availability. ## Methods: We studied 219 patients with PD who were free of dyskinesias at baseline and underwent t