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Effects of the recreational use of PDE5 inhibitors on the corpus cavernosum of young, healthy rats

✍ Scribed by Simsek, Abdulmuttalip; Tugcu, Volkan; Erturkuner, Pelin; Alkan, Faruk; Ozbek, Emin; Tasci, Ali Ihsan


Book ID
125370178
Publisher
Springer Netherlands
Year
2014
Tongue
English
Weight
512 KB
Volume
46
Category
Article
ISSN
0301-1623

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Pharmacological characterization of the
✍ Gilberto De Nucci; Raquel Lorenzetti; Cristina E Okuyama; Juliana S Baracat; Jos πŸ“‚ Article πŸ“… 2007 πŸ› BioMed Central 🌐 English βš– 785 KB

## Background Nitrergic nerves and endothelial cells release nitric oxide (NO) in the corpus cavernosum (CC), a key mediator that stimulates soluble guanylyl cyclase to increase cGMP levels and cause penile erection. Phosphodiesterase 5 (PDE5) inhibitors, such as sildenafil, prolong NO effects by