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Effects of the Progestin Antagonist RU 486 on T-47D Breast Cancer Cell Cycle Kinetics and Cell Cycle Regulatory Genes

✍ Scribed by E.A. Musgrove; R.L. Sutherland


Book ID
115573544
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
356 KB
Volume
195
Category
Article
ISSN
0006-291X

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The replication of several human and animal cancer cell lines is regulated in vitro and in vivo by 1,25-dihydroxyvitamin D3 I 1 ,25-(OH),D3], the hormonally active form of vitamin Uj. We have examined the effects of concentrations of 1 ,25-(OH)2D3, which inhibit cellular replication, on the cell-cyc