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Effects of 1,25-dihydroxyvitamin D3 on cell-cycle kinetics of T 47D human breast cancer cells

✍ Scribed by John A. Eisman; Robert L. Sutherland; M. Lynne McMenemy; Jean-Charles Fragonas; Elizabeth A. Musgrove; Grace Y. N. Pang

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
618 KB
Volume
138
Category
Article
ISSN
0021-9541

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✦ Synopsis

The replication of several human and animal cancer cell lines is regulated in vitro and in vivo by 1,25-dihydroxyvitamin D3 I 1 ,25-(OH),D3], the hormonally active form of vitamin Uj. We have examined the effects of concentrations of 1 ,25-(OH)2D3, which inhibit cellular replication, on the cell-cycle kinetics of a

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