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Effects of the Novel D1 Dopamine Receptor Agonist ABT-431 on Cocaine Self-Administration and Reinstatement

✍ Scribed by DAVID W. SELF; DAVID A. KARANIAN; JENNIFER J. SPENCER

Book ID
118724371
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
488 KB
Volume
909
Category
Article
ISSN
0890-6564

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An array of evidence indicates that long-term exposure to cocaine alters several components of the brain dopamine system. Because the release of dopamine in the nucleus accumbens (NAc) has been implicated in mediating the reinforcing effects of cocaine, changes in dopamine function can have profound