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Effects of selenium on the mutagenicity of 2-acetylaminofluorene (AAF) and AAF metabolites

โœ Scribed by M.M. Jacobs; T.S. Matney; A.C. Griffin

Book ID
113249486
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
129 KB
Volume
53
Category
Article
ISSN
0165-1161

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Restriction site mutation (RSM) analysis
Restriction site mutation (RSM) analysis of 2-acetylaminofluorene (2-AAF)-induced mouse liver mutations and comparison with the measurement of in vivo micronucleus induction in the bone marrows of (2-AAF)-treated mice
โœ G.J.S. Jenkins; J.M. Parry ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 80 KB ๐Ÿ‘ 2 views

We report here the successful application of the restriction site mutation (RSM) assay in detecting 2-acetylaminofluorene (2-AAF)-induced mouse liver mutations. A total of seven 2-AAF-induced liver mutations were detected out of a total of 304 analyses performed on 2-AAF-treated liver tissue. No mut