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Inhibitory effects of selenium on the mutagenicity of 2-acetylaminofluorene (AAF) and AAF derivatives

✍ Scribed by JACOBS, M; MATNEY, T; GRIFFIN, A

Book ID
124131417
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
206 KB
Volume
2
Category
Article
ISSN
0304-3835

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Restriction site mutation (RSM) analysis
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We report here the successful application of the restriction site mutation (RSM) assay in detecting 2-acetylaminofluorene (2-AAF)-induced mouse liver mutations. A total of seven 2-AAF-induced liver mutations were detected out of a total of 304 analyses performed on 2-AAF-treated liver tissue. No mut