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Effects of rifampicin and phenobarbital on the fate of isoniazid and hydrazine in vivo in rats

โœ Scribed by Noda, A.; Sendo, T.; Ohno, K.; Goto, S.; Noda, H.; Hsu, K-Y.

Book ID
123541097
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
330 KB
Volume
25
Category
Article
ISSN
0378-4274

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The effect of rifampicin and pyrazinamid
The effect of rifampicin and pyrazinamide on isoniazid pharmacokinetics in rats
โœ Helen M. Baldan; Helene J. De Rosa; Iguatemy L. Brunetti; Valdecir F. Ximenes; R ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 99 KB ๐Ÿ‘ 2 views

Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo