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Effect of Erythromycin, Rifampicin and Isoniazid on the Pharmacokinetics of Quinine in Rats

โœ Scribed by HU ZHANG; NICOLA RAMSAY; PETER F. COVILLE; SOMPON WANWIMOLRUK


Book ID
111770145
Publisher
Pharmaceutical Press
Year
1999
Tongue
English
Weight
73 KB
Volume
5
Category
Article
ISSN
2042-7158

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The effect of rifampicin and pyrazinamid
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Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo