𝔖 Bobbio Scriptorium
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Effects of phenobarbital pretreatment on the in vivo metabolism of carbaryl in rats

✍ Scribed by E. V. Knight; A. P. Alvares; B. H. Chin


Book ID
112639887
Publisher
Springer
Year
1987
Tongue
English
Weight
304 KB
Volume
39
Category
Article
ISSN
0007-4861

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Effect of phenobarbital pretreatment on
✍ I. Gut πŸ“‚ Article πŸ“… 1976 πŸ› Springer-Verlag 🌐 English βš– 704 KB

Phenobarbital pretreatment (50 mg/kg/day for 3 days orally) of male Wistar rats increased Vmax of benzene in vitro hepatic microsomal biotransformation about 6-fold without changing Km. However, benzene blood levels after oral, intraperitoneal, or subcutaneous benzene administration (3-3.5 mmoles/kg