𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of phenobarbital pretreatment on benzene biotransformation in the rat

✍ Scribed by I. Gut; K. Hátle; L. Žižková


Publisher
Springer-Verlag
Year
1981
Tongue
English
Weight
610 KB
Volume
47
Category
Article
ISSN
0340-5761

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Effect of phenobarbital pretreatment on
✍ I. Gut 📂 Article 📅 1976 🏛 Springer-Verlag 🌐 English ⚖ 704 KB

Phenobarbital pretreatment (50 mg/kg/day for 3 days orally) of male Wistar rats increased Vmax of benzene in vitro hepatic microsomal biotransformation about 6-fold without changing Km. However, benzene blood levels after oral, intraperitoneal, or subcutaneous benzene administration (3-3.5 mmoles/kg

Effects of phenobarbital and 3-methylcho
✍ Young M. Choi; Sun H. Lee; Seong H. Jang; Myung G. Lee 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 653 KB

The effects of pretreatment with the enzyme inducers, phenobarbital (PB) and 3-methylcholanthrene (3-MC), on the pharmacokinetic and pharmacodynamic parameters of bumetanide were examined in rats. The nonrenal clearance (19.3 vs 29.6 ml min-' per kg) of bumetanide increased significantly in PB treat

EFFECT OF PHENOBARBITAL, 3-METHYLCHOLANT
✍ SUN H. LEE; MYUNG G. LEE 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB 👁 2 views

The eects of pretreatment with the enzyme inducers phenobarbital (PB) and 3methylcholanthrene (3-MC) and the enzyme inhibitor chloramphenicol (CM) on the pharmacokinetic and pharmacodynamic parameters of azosemide were examined after intravenous (IV) administration of azosemide, 10 mg kg 71 , to rat