✦ LIBER ✦

Effects of repeated caffeine administration on cognition and mood

✍ Scribed by Wing Hong Loke

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 790 KB
Volume: 5
Category: Article
ISSN: 0885-6222
DOI: 10.1002/hup.470050406

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✦ Synopsis

Abstract

The effects of repeated caffeine administration on cognitive and mood tasks were investigated in a double‐blind study of 32 young healthy adults who were randomly assigned to one of the four treatment conditions: 0, 200, 400, or 600 mg of caffeine. Subjects were tested over six alternate days; on each test day they completed various tasks after drug administration. In general, caffeine produced no significant effects on cognitive performance; the exception is that the highest dose (600 mg) reduced the speed of completion of additions relative to the other doses. Also, post‐hoc analysis showed that the highest dose impaired performance of the lower caffeine users more than higher users. Mood assessment showed individuals were sensitive to the effects of caffeine but the effect did not interact with cognitive performance. The present data suggest that tolerance to the cognitive effects of caffeine does not develop with continued caffeine administration, given the limitations that the individuals tested were young healthy adults and the testing took place only over 2 weeks.

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