## SUMMARY Cognitive impairment has emerged as a major driver of disability in old age, with profound effects on individual wellβbeing and decision making at older ages. In the light of policies aimed at postponing retirement ages, an important question is whether continued labour supply helps to m
The effect of vigabatrin on cognitive function and mood
β Scribed by J. B. Dijkstra; A. M. McGuire; M. R. Trimble
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 386 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0885-6222
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Cognitive function and mood have been assessed in nine patients started on vigabatrin as additional therapy to their regular anticonvulsants. Psychological tests were given at baseline (S1) and at 4 weeks (S2) after starting treatment. A comparison group of nine patients on stable therapy was tested at the same time intervals. In particular, tasks with minimal or no motor components were used. Mood was rated with the Beck Depression Inventory. The vigabatrin group scored significantly higher on a task of attention and concentration at S2. This was not related to change of seizure frequency or serum levels of other anticonvulsants. No effects were observed on mood.
π SIMILAR VOLUMES
Treatments available for depression vary in their side-eects. Behavioural toxicity, the alteration of psychomotor performance and cognitive function, can be counter-therapeutic, especially in elderly patients or those already cognitively compromised by their illness. This double-blind, 10-way crosso
An experiment was conducted to examine the eects of caeine and noise on mood, mental performance and cardiovascular function. One hundred and six young adults (mean age 21 . 2 years) took part in the study. Subjects were assigned to one of six groups formed by combining noise/quiet and drink (caeina
Lithium, despite its simple structure, has numerous biological effects. It also has a remarkable therapeutic effect in the prophylactic treatment of manic depression, and is finding a role in controlling aggressive and self-mutilating behavior. The special feature of lithium is that it only acts on