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Effects of protein phosphorylation on ubiquitination and stability of the translational inhibitor protein 4E-BP1

✍ Scribed by Constantinou, C; Clemens, M J; Elia, A


Book ID
110072668
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
319 KB
Volume
27
Category
Article
ISSN
0950-9232

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Increased phosphorylation of the translational repressor protein 4E-BP1 was found in the cell line derived from the tumor induced in Syrian hamster by Rous sarcoma virus (RSV). This was accompanied by its dissociation from the complex with initiation factor eIF4E. The ribosomal S6 protein kinase p70