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Effects of prednisolone on esterases in heteroploid cells of human origin

✍ Scribed by Melnykovych, G.; Swayze, M.A.; Bishop, C.; Costlow, C.

Book ID
122539135
Publisher
Elsevier Science
Year
1969
Tongue
English
Weight
198 KB
Volume
184
Category
Article
ISSN
0304-4165

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## Abstract Prednisolone‐induced alterations in the content and composition of the total lipids, cholesterol, phospholipids and fatty acids were studied in HeLa S3 cells. After relatively long exposure of the cell cultures to the hormone analog (24 to 72 hours), total cell lipid content was decreas

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In two heteroploid cell lines synchronized with thymidine double block, activity of alkaline phosphatase decreased during the 12 hour period preceding mitotic peak. A return to high values was observed during the next 12 hours of synchronous cycle. Prednisolone ( llp, 17a, 21-trihydroxy-1,4-pregnadi