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Effects of pimozide on sucrose consumption and preference

✍ Scribed by A. Towell; R. Muscat; P. Willner

Publisher
Springer
Year
1987
Tongue
English
Weight
350 KB
Volume
92
Category
Article
ISSN
0033-3158

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✦ Synopsis

The effects of pimozide on sucrose intake were examined, in a two-bottle preference test (sucrose versus water), and in single-bottle tests at five different sucrose concentrations. In the two-bottle test, pimozide dose dependently decreased sucrose intake but increased water intake. In the single-bottle test pimozide decreased sucrose intake at low concentrations but had no effect at high concentrations. The results support a role for dopamine in mediating the rewarding effect of sucrose.

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