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Effects of Monoglycerides on P-Glycoprotein: Modulation of the Activity and Expression in Caco-2 Cell Monolayers

✍ Scribed by Barta, Cheri A.; Sachs-Barrable, Kristina; Feng, Florina; Wasan, Kishor M.


Book ID
127054225
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
254 KB
Volume
5
Category
Article
ISSN
1543-8384

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P-glycoprotein–mediated transport of ber
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The objective of this study was to investigate the mechanisms by which berberine is transported in the secretory and absorptive directions across Caco-2 cell monolayers. The basolateral-to-apical (B-A) flux was 30-fold greater than the apical-to-basolateral flux and temperature dependent (i.e., dras