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Age-dependent Expression of P-Glycoprotein gp17O in Caco-2 Cell Monolayers

✍ Scribed by Ken-ichi Hosoya; Kwang-Jin Kim; Vincent H. L. Lee

Book ID
110343827
Publisher
Springer US
Year
1996
Tongue
English
Weight
841 KB
Volume
13
Category
Article
ISSN
0724-8741

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The objective of this study was to investigate the mechanisms by which berberine is transported in the secretory and absorptive directions across Caco-2 cell monolayers. The basolateral-to-apical (B-A) flux was 30-fold greater than the apical-to-basolateral flux and temperature dependent (i.e., dras