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Effects of Methylcholanthrene and Colchicine administered with Plant Extracts on the Rat

✍ Scribed by HAVAS, LÁSZLÓ; GAL, EMERY


Book ID
109523200
Publisher
Nature Publishing Group
Year
1938
Tongue
English
Weight
223 KB
Volume
141
Category
Article
ISSN
0028-0836

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The effects of pretreatment with the enzyme inducers, phenobarbital (PB) and 3-methylcholanthrene (3-MC), on the pharmacokinetic and pharmacodynamic parameters of bumetanide were examined in rats. The nonrenal clearance (19.3 vs 29.6 ml min-' per kg) of bumetanide increased significantly in PB treat