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Effects of metformin on mouse oocyte maturation in vitro

โœ Scribed by M.E. Sabatini; B.R. Rueda; H.-J. Lee

Book ID
116472262
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
68 KB
Volume
88
Category
Article
ISSN
1556-5653

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## Abstract The effects of dibutyryl cyclic AMP on the maturation of the mouse oocyte in vitro were studied. It was found that concentrations of 100 ฮผg/ml or greater prevented germinal vesicle breakdown in more than 95% of the treated oocytes. The inhibition of maturation was found to be a reversib