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Effects of infantile handling on morphological development of the rat brain: An exploratory study

✍ Scribed by Joseph Altman; Gopal D. Das; William J. Anderson

Publisher: John Wiley and Sons
Year: 1968
Tongue: English
Weight: 1002 KB
Volume: 1
Category: Article
ISSN: 0012-1630
DOI: 10.1002/dev.420010104

No coin nor oath required. For personal study only.

✦ Synopsis

J . (196s). Eflects of Znfnnlile Hnndliiig on Morphological hantlled daily from day 2 to I 1 after birth, inclusive. These animals and unhantlled controls were injected on day 11 with a radioactive1~-labeled precursor of deoxyribonucleic acid (DNA) and killed eithcr 6 hr, 3 or 30 days later. I n a subsequcnt experiment, uninjccted rats were likewise permitted to survive until 11, 14, 41, or 101 d a y of age. Brain weight tneasurcnicnts were taken in all aniinals, and the brains from the rats of the first experinic'nt prepared for histology and autoradiography, and cvaluated quantitatively.

T h c following differrnces were established: (I) The brains of the handled rats were consistently lighter than

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