The K+ channel blocker 4-aminopyridine (4-AP) causes epileptiform activity in in vitro preparations and is a potent convulsant in animals and man. In mice, 4-AP produces behavioral activation, clonic limb movements and wild running, followed by tonic hindlimb extension and death (ED97, 13.3 mg/kg, s
Effects of gamma-decanolactone on seizures induced by PTZ-kindling in mice
✍ Scribed by Paulo Alexandre de Oliveira; Felipe Luis Lino; Shandale Emanuele Cappelari; Lucimar Filot da Silva Brum; Jaqueline Nascimento Picada; Patrícia Pereira
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 295 KB
- Volume
- 187
- Category
- Article
- ISSN
- 0014-4819
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