The K+ channel blocker 4-aminopyridine (4-AP) causes epileptiform activity in in vitro preparations and is a potent convulsant in animals and man. In mice, 4-AP produces behavioral activation, clonic limb movements and wild running, followed by tonic hindlimb extension and death (ED97, 13.3 mg/kg, s
Effects of some GABAergic agents on quinine-induced seizures in mice
โ Scribed by G. J. Amabeoku; O. Chikuni
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 378 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1420-682X
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