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Effects of felbamate on the pharmacokinetics of phenobarbital

✍ Scribed by Reidenberg, Pascale; Glue, Paul; Banfield, Christopher R.; Colucci, Robert D.; Meehan, Jeffrey W.; Radwanski, Elaine; Mojavarian, Parviz; Lin, Chin-Chung; Nezamis, James; Guillaume, Michel; Affrime, Melton B.

Book ID
107740718
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
880 KB
Volume
58
Category
Article
ISSN
0009-9236

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## Abstract In order to determine interaction of smoking with single dose pharmacokinetics of phenobarbital, a 60 mg tablet of the drug was given to 12 healthy male subjects in two groups (6 smokers and 6 non‐smokers) in a double blind study. An HPLC method using UV detection was developed to asses