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Effects of capsaicin on human intestinal cell line Caco-2

✍ Scribed by Hiroko Isoda; Junkyu Han; Makoto Tominaga; Takaaki Maekawa

Book ID
110326725
Publisher
Springer
Year
2001
Tongue
English
Weight
135 KB
Volume
36
Category
Article
ISSN
0920-9069

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Transport of levovirin prodrugs in the h
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The transport of 10 amino acid ester prodrugs of levovirin (LVV) was investigated in the human intestinal Caco-2 cell line in order to overcome the poor oral bioavailability of LVV, an investigational drug for the treatment of hepatitis C infection. The prodrugs were designed to improve the permeabi