𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effects of borneol on the intestinal transport and absorption of two P-glycoprotein substrates in rats

✍ Scribed by Huijuan He; Qi Shen; Jian Li

Book ID
107642510
Publisher
Springer
Year
2011
Tongue
English
Weight
609 KB
Volume
34
Category
Article
ISSN
0253-6269

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Lipid formulation strategies for enhanci
Lipid formulation strategies for enhancing intestinal transport and absorption of P-glycoprotein (P-gp) substrate drugs: In vitro/In vivo case studies
✍ Panayiotis P. Constantinides; Kishor M. Wasan πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 277 KB πŸ‘ 1 views

The intestinal efflux pump, P-glycoprotein (P-gp), located in the apical membranes of intestinal absorptive cells, can reduce the bioavailability of a wide range of drugs which are substrates for this membrane transporter. In addition to anticancer and anti-HIV drugs, NCEs for other disease indicati

Prediction of in vivo intestinal absorpt
Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability
✍ Manthena V.S. Varma; Ramesh Panchagnula πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 180 KB πŸ‘ 1 views

The purpose of this study is to determine the functional role of P-glycoprotein (P-gp) in intestinal absorption of drugs and to quantitatively predict the in vivo absorption enhancement on P-gp inhibition. In situ single-pass rat ileum permeability and aqueous solubility were measured for a set of 1