✦ LIBER ✦

Involvement of intestinal P-glycoprotein in the restricted absorption of methylprednisolone from rat small intestine

✍ Scribed by Hiroshi Saitoh; Masataka Hatakeyama; Orie Eguchi; Masako Oda; Masahiko Takada

Book ID: 109388858
Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 88 KB
Volume: 87
Category: Article
ISSN: 0022-3549
DOI: 10.1021/js970163u

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Role of P-glycoprotein as a secretory me

Role of P-glycoprotein as a secretory mechanism in quinidine absorption from rat small intestine

✍ Yasuharu Emi; Daisuke Tsunashima; Ken-Ichi Ogawara; Kazutaka Higaki; Toshikiro K 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

Characterization of ethiofos absorption

Characterization of ethiofos absorption in the rat small intestine

✍ Richard S. Geary; Nollie F. Swynnerton; Scott F. Timmons; Donald J. Mangold 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 728 KB

The absorption characteristics of ethiofos were studied using the rat in situ intestine circulating perfusion technique. Slow absorption kinetics were observed for ethiofos with varying rates of absorption and metabolisddegradation in situ as a function of buffer and absorption enhancers. In most ca

Intestinal absorption of 5-fluorouracil

Intestinal absorption of 5-fluorouracil and its alkylcarbamoyl derivatives in the rat small intestine

✍ Hitoshi Sasaki; Tohru Takahashi; Junzo Nakamura; Ryoji Konishi; Juichiro Shibasa 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 419 KB

The effects of PLGA microparticles on in

The effects of PLGA microparticles on intestinal absorption of p-glycoprotein substrate using the everted rat intestinal sac model

✍ Katayoun Derakhshandeh; Aidin Hosseinalizadeh; Maryam Nikmohammadi 📂 Article 📅 2011 🏛 Springer 🌐 English ⚖ 613 KB

Prediction of in vivo intestinal absorpt

Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability

✍ Manthena V.S. Varma; Ramesh Panchagnula 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB 👁 1 views

The purpose of this study is to determine the functional role of P-glycoprotein (P-gp) in intestinal absorption of drugs and to quantitatively predict the in vivo absorption enhancement on P-gp inhibition. In situ single-pass rat ileum permeability and aqueous solubility were measured for a set of 1

Characterization of WR-1065 absorption i

Characterization of WR-1065 absorption in the rat small intestine

✍ R. S. Geary; N. F. Swynnerton; S. F. Timmons; D. J. Mangold 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 479 KB 👁 2 views

A circulating in situ rat small intestine absorption model was used to study the lumenal metabolism and absorption of ['4C]WR-1065. WR-1065 was found to be more tissue reactive and toxic than its phosphorylated form, ethiofos, at equimolar perfusate concentrations. The disappearance profiles of the